Table 1.

Body weight (g)	eNOS KO
	Non-DM			DM
	No treatment	Enalapril	Telmisartan	No treatment	Enalapril	Telmisartan
	26.1 ± 2.25	27.2 ± 2.0	27.6 ± 1.54	18.7 ± 2.87*	17.9 ± 0.30†	18.5 ± 3.56‡
Blood sugar (mg/dl)	112 ± 10	108 ± 12	104 ± 14	276 ± 26*	281 ± 49†	270 ± 37‡
Systolic BP (mm Hg)	142 ± 3.8	116 ± 6.1*	112 ± 8.3*	152 ± 8.8	148 ± 9.9†	138 ± 13‡§
Kidney/body weight (10−3)	5.3 ± 0.79	5.0 ± 0.61	5.3 ± 0.86	10.3 ± 2.19*	9.3 ± 1.32†	9.4 ± 2.91‡
Serum creatinine (mg/dl)	0.055 ± 0.042	0.13 ± 0.090	0.10 ± 0.099	0.18 ± 0.13	0.18 ± 0.076	0.17 ± 0.14
Serum K (mmol/L)	4.8 ± 0.77	5.2 ± 0.53	4.6 ± 1.3	4.2 ± 1.1	4.2 ± 1.0	3.9 ± 0.33
Urine albumin/creatinine	0.12 ± 0.054	0.072 ± 0.017	0.04 ± 0.019	2.3 ± 2.3¶	1.4 ± 0.89	0.71 ± 0.47

Data are means ± SD (n = 10); BP, blood pressure. 

^*P < 0.001 versus non-DM no treatment. 

^†P < 0.001 versus non-DM enalapril. 

^‡P < 0.001 versus non-DM telmisartan. 

^§P < 0.05 versus DM no treatment. 

^¶P < 0.005 versus non-DM no treatment.