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. 2010 Feb;176(2):650–659. doi: 10.2353/ajpath.2010.090447

Figure 2.

Figure 2

The protein level of Notch signaling components was increased in fibrotic peritoneum induced by PDF. A: Normal rats (A1 to A6) or rats that received daily intraperitoneal injections of 4.25% Dianeal (100 ml/kg) for 14 days (B1 to B6) or 28 days (C1 to C6) were sacrificed. The protein levels of NICD, Jagged-1, and HES-1 were analyzed by Western blot. GAPDH was used to verify equivalent loading. Each panel represents an independent experiment with two animals per group. B: Graphic representation of relative abundance of NICD, Jagged-1, and HES-1 normalized to GAPDH. Data are given as mean ± SD (n = 6). *P < 0.05 versus normal rats. **P < 0.01 versus normal rats.