Figure 15.

Double immunohistochemical observation of intercalated disk at I and IV-mode. N-cadherin and myosin (N-cadherin+myosin) and N-cadherin and actin (N-cadherin+HHF35) are double immunohistochemically stained in control (I-mode) and 1 day after AVF (IV-mode). N-cadherin stained ICD is narrow and simple interposed between two myosin lines and actin lines in I-mode. N-cadherin stained ICD is wide and irregular in IV-mode. The zone margined by myosin or actin is filled with irregular and widened ICDs. Some actin positive portions appear within ICDs.