Table 1.

Morphometric Data from Hearts

	Sham (n = 10)	DOX + LacZ (n = 10)	DOX + sFas (n = 10)
Heart weight (mg)	95 ± 2.1	81 ± 4.3*	83 ± 3.1*
Body weight (g)	26 ± 0.4	23 ± 0.7*	22 ± 0.7*
Heart to body weight ratio (mg/g)	3.7 ± 0.06	3.6 ± 0.13	3.7 ± 0.17
Size of myocyte (μm)	14.0 ± 0.2	12.3 ± 0.1*	12.6 ± 0.3*
CD45+ cells (/HPF)	4.4 ± 0.28	7.6 ± 0.41*	4.8 ± 0.34*†
% fibrosis	0.46 ± 0.02	1.04 ± 0.07*	0.73 ± 0.06*†
8-OHdG+ cells (/HPF)	1.5 ± 0.1	16 ± 0.2*	4.5 ± 0.1*†

DOX, doxorubicin. 

^*P < 0.05 versus the sham group. 

^†P < 0.05 versus the LacZ-treated group.