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. 2009 Nov 6;115(2):370–378. doi: 10.1182/blood-2009-03-210369

Figure 5.

Figure 5

Effects of ADAMTS-13 concentration. Time-to-rupture t11 (A), time-to-destabilization t21 (B), and time-to-rupture t22 of the short (C) and long (D) groups were plotted versus ADAMTS-13 concentration. With the exception of t22, which was shortened by ADAMTS-13 in a dose-dependent manner, other time parameters were indifferent to the changing ADAMTS-13 concentration. DisC is a control construct without VWF-cleaving activity. Data were acquired by GPIbα-pulling and presented as mean ± SEM of several tens of measurements.