Fig. 2.

Heat map showing distinct gene expression patterns in pretreatment and on-treatment groups. The map is based on the 364 genes with a greater than 1.5-fold difference in the expression with P <0.01. Red indicates increased gene expression, and blue indicates decreased gene expression. The white line across and down the heat map provides a statistically significant separation of the 2 groups and up-regulated or down-regulated genes. Within the 2 groups, the treatment response is indicated as follows: N, naive treatment; RR, rapid responder; and SR, slow responder.