Table 3.
Gene Category | Gene Name | Gene Symbol | Fold Change (RR/SR) | P |
---|---|---|---|---|
ISG | 2′,5′-Oligoadenylate synthetase 2*† | OAS2 | −2.4 | 0.02 |
2′,5′-Oligoadenylate synthetase 3*† | OAS3 | −2.4 | 0.01 | |
IFN-induced transmembrane protein 1 | IFITM1 | −2.3 | 0.001 | |
IFN-induced transmembrane protein 3 | IFITM3 | −1.5 | 0.004 | |
IFN-alpha–inducible protein (ISG-15)*† | G1P2/ISG15 | −3.2 | 0.028 | |
IFN-alpha–inducible protein (IFI-6–16)† | G1P3/IFI6 | −3.0 | 0.0016 | |
IFN-alpha–inducible protein 27 | IFI27 | −3.7 | 0.004 | |
IFN-induced protein 35 | IFI35 | −2.3 | 0.0048 | |
IFN-induced protein 44 | IFI44 | −2.7 | 0.001 | |
IFN-induced protein with TTPR 1† | IFIT1 | −2.8 | 0.01 | |
IFN-induced protein with TTPR 3 | IFIT3 | −2.6 | 0.0075 | |
Myxovirus resistance 1† | MX1 | −3.9 | 0.0004 | |
Phospholipid scramblase 1 | PLSCR1 | −2.0 | 0.003 | |
Ubiquitin-specific peptidase 18*† | USP18 | −1.7 | 0.042 | |
Viperin† | RSAD2 | −3.3 | 0.0008 | |
IFN-Related | RIG-I DEAD box polypeptide 58 | DDX58 | −2.0 | 0.01 |
Signal transducer activator of transcription 1 | STAT1 | −2.0 | 0.0048 | |
Other | Activating transcription factor 7 interacting protein 2† | ATF7IP2 | 1.7 | 0.0083 |
Chemokine ligand 9 (MIG) | CXCL9 | 2.9 | 0.0062 | |
Leucine aminopeptidase 3*† | LAP3 | −1.5 | 0.030 | |
Ribosomal protein S28† | RPS28 | 1.98 | 0.0077 | |
Syntaxin binding protein 5-like† | STXBP5L | 6.4 | 0.0003 |
P between 0.05 and 0.01.
Gene identified by Chen et al.6 as differing between future sustained responders and future nonresponders. Abbreviations: IFN, interferon; ISG, interferon-stimulated gene.