Table I.
Characteristics of multiple myeloma cases and controls.
| All sites | Detroit | Connecticut | Seattle | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Characteristic | Cases (n=279) |
Controls (n=782) |
p- value* |
Cases (n=77) |
Controls (n=96) |
p- value* |
Cases (n=151) |
Controls (n=564) |
p- value* |
Cases (n=51) |
Controls (n=122) |
p- value* |
|
Age at diagnosis or selection, yrs |
||||||||||||
| 35–49 | 30 (11%) |
172 (22%) |
14 (18%) |
27 (28%) |
9 (6.0%) |
115 (20%) |
7 (14%) |
30 (25%) |
||||
| 50–59 | 73 (26%) |
159 (20%) |
29 (38%) |
23 (24%) |
33 (22%) |
101 (18%) |
11 (22%) |
35 (29%) |
||||
| 60–69 | 88 (32%) |
203 (26%) |
21 (27%) |
36 (38%) |
45 (30%) |
128 (23%) |
22 (43%) |
39 (32%) |
||||
| 70–75 | 88 (32%) |
248 (32%) |
0.0002 | 13 (17%) |
10 (10%) |
0.07 | 64 (42%) |
220 (39%) |
0.0004 | 11 (22%) |
18 (15%) |
0.18 |
| Gender | ||||||||||||
| Male | 77 (28%) |
117 (15%) |
48 (62%) |
52 (54%) |
0 | 0 | 29 (57%) |
65 (53%) |
||||
| Female | 202 (72%) |
665 (85%) |
<0.0001 | 29 (38%) |
44 (46%) |
0.28 | 151 | 564 | -- | 22 (43%) |
65 (47%) |
0.67 |
| Race | ||||||||||||
| Caucasian | 233 (84%) |
726 (93%) |
52 (68%) |
60 (63%) |
131 (87%) |
548 (97%) |
50 (98%) |
118 (97%) |
||||
|
African American |
46 (16%) |
56 (7.2%) |
<0.0001 | 25 (32%) |
36 (37%) |
0.49 | 20 (13%) |
16 (2.8%) |
<0.0001 | 1 (2.0%) |
4 (3.3%) |
0.99 |
| Education, yrs | ||||||||||||
| 0–11 | 47 (17%) |
80 (10%) |
12 (16%) |
14 (15%) |
28 (19%) |
63 (11%) |
7 (14%) |
3 (2.5%) | ||||
| 12–15 | 160 (58%) |
429 (55%) |
46 (60%) |
48 (50%) |
92 (61%) |
308 (55%) |
22 (43%) |
73 (60%) |
||||
| 16 or more | 71 (25%) |
273 (35%) |
0.001 | 18 (24%) |
34 (35%) |
0.24 | 31 (20%) |
193 (34%) |
0.002 | 22 (43%) |
46 (38%) |
0.007 |
*
p-value from chi-square or Fisher’s exact statistic comparing case and control distributions