Table 1. Characteristics of patients included in the study.
| Multiple CRC (n = 41) | Solitary CRC (n = 41) | P value1 | |
| Age (yrs.)2 | 74.3±8.2 | 74.9±9.1 | 0.97 |
| Gender –no. (%) | 0.82 | ||
| male | 28 (68.3%) | 26 (63.4%) | |
| female | 13 (31.7%) | 15 (36.6%) | |
| Tumor location –no. (%)3 | 1.0 | ||
| right | 25 (61.0%) | 25 (61.0%) | |
| left | 16 (39.0%) | 16 (39.0%) | |
| Tumor stage –no. (%)3 | 0.82 | ||
| I | 4 (9.8%) | 5 (12.1%) | |
| II | 15 (36.6%) | 19 (46.3%) | |
| III | 13 (31.7%) | 12 (29.3%) | |
| IV | 7 (17.1%) | 5 (12.2%) | |
| Tumor multiplicity –no. (%) | - | ||
| synchronous | 36 (87.8%) | NA | |
| metachronous | 4 (9.8%) | NA | |
| both | 1 (2.4%) | NA | |
| Synchronous adenoma –no. (%) | 25 (61.0%) | 1 (2.4%) | 0.001 |
| Personal history of other neoplasms –no. (%)4 | 1 (2.4%) | 1 (2.4%) | 1.0 |
| Family history of colorectal cancer –no. (%)5 | 5 (12.2%) | 7 (17.1%) | 0.76 |
| Family history of other neoplasms –no. (%)5 | 2 (4.9%)6 | 5 (12.2%) | 0.43 |
| endometrial | 2 | 1 | |
| gastric | 1 | 3 | |
| ovary | - | 1 | |
| Tumor DNA mismatch repair deficiency –no. (%) | 3 (7.3%) | 2 (4.9%) | 0.64 |
CRC, colorectal cancer; NA, not applied.
1
Qualitative variables were compared by the Fisher's exact test; continuous variables were compared by the Mann-Whitney U's test.
2
Results expressed as mean ± standard deviation.
3
In patients with multiple tumors, characteristics were referred to the most advanced lesion.
4
Other neoplasms included small bowel and ovary, respectively.
5
Family history was referred to first degree relatives.
6
One patient had both endometrial and gastric cancer.