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. Author manuscript; available in PMC: 2010 Jan 20.
Published in final edited form as: Biochim Biophys Acta. 2005 Feb 14;1727(2):125–133. doi: 10.1016/j.bbaexp.2004.12.007

Fig. 7.

Fig. 7

Role of CACCC motifs for the activity of KLF13 on its own promoter. They were disrupted by the point mutations listed in Table 1. Promoters lacking the −0.37 kb, −0.23 kb and both CACCC motifs are referred to CACCCmut1, CACCCTmut2 and CACCCmut3, respectively, which are shown in the left panel. The numbers shown above are the distance to the transcription start site in kb. Right panel shows relative luciferase activities tested in K562 cells. Luciferase counts were corrected by the β-Gal activity, and the average count of wild type (WT) promoter without co-expressed KLF13 was considered as 100%. Error bars indicate one S.D. The solid lines shown at the right indicate that the promoter activities were significantly different. Results were obtained from five independent transfections in triplicate.