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. 2010 Jan 20;98(2):231–239. doi: 10.1016/j.bpj.2009.10.015

Figure 9.

Figure 9

Relationship between water permeability and leak current. (A) Effect of mutations C292A and C610A on LP and the leak current (at −155 mV) relative to wt SGLT1 after correcting for plasma membrane expression level. (B) Immunocolorimetric detection of plasma membrane expression levels of wt SGLT1 (n = 4, where each is a group of 5–12 oocytes), C292A (n = 2) and C610A (n = 2). Noninjected oocytes (n = 4) as well as oocytes expressing the human Na+/myo-inositol cotransporter 2 (hSMIT2) (n = 2) were used as negative controls. Mean ± SE are shown.