Table 1.
Selected Characteristics of Lung Cancer Cases and Controls With Interview Data Available, the EAGLE Study, Lombardy, Italy, 2002–2005a,b
| Women |
Men |
|||||||
| Cases |
Controls |
Cases |
Controls |
|||||
| No. | % | No. | % | No. | % | No. | % | |
| Total participants enrolled | 448 | 500 | 1,652 | 1,620 | ||||
| Interviewed | 406 | 100.0 | 499 | 100.0 | 1,537 | 100.0 | 1,617 | 100.0 |
| Area of residence | ||||||||
| Milan | 288 | 70.9 | 349 | 69.9 | 987 | 64.2 | 1,089 | 67.3 |
| Monza | 24 | 5.9 | 23 | 4.6 | 109 | 7.1 | 94 | 5.8 |
| Brescia | 47 | 11.6 | 53 | 10.6 | 203 | 13.2 | 194 | 12.0 |
| Pavia | 21 | 5.2 | 37 | 7.4 | 107 | 7.0 | 92 | 5.7 |
| Varese | 26 | 6.4 | 37 | 7.4 | 131 | 8.5 | 148 | 9.2 |
| P = 0.55 | P = 0.17 | |||||||
| Age, years (mean (SD)) | 64.8 (10.1) | 64.1 (10.1) | 66.8 (7.9) | 65.8 (8.1) | ||||
| P = 0.32 | P < 0.001 | |||||||
| Educational level | ||||||||
| None | 21 | 5.2 | 24 | 4.8 | 91 | 5.9 | 66 | 4.1 |
| Elementary school | 128 | 31.5 | 143 | 28.7 | 625 | 40.7 | 431 | 26.7 |
| Middle school | 134 | 33.0 | 158 | 31.7 | 424 | 27.6 | 455 | 28.1 |
| High school | 104 | 25.6 | 135 | 27.1 | 314 | 20.4 | 441 | 27.3 |
| University | 19 | 4.7 | 39 | 7.8 | 83 | 5.4 | 224 | 13.9 |
| P = 0.35 | P < 0.001 | |||||||
| No. of jobs held | ||||||||
| 1 | 166 | 40.9 | 168 | 33.7 | 375 | 24.4 | 370 | 22.9 |
| 2 | 96 | 23.7 | 158 | 31.7 | 404 | 26.3 | 356 | 22.0 |
| 3 | 77 | 19.0 | 82 | 16.4 | 305 | 19.8 | 356 | 22.0 |
| 4 | 30 | 7.4 | 49 | 9.8 | 194 | 12.6 | 226 | 14.0 |
| ≥5 | 37 | 9.1 | 42 | 8.4 | 259 | 16.9 | 309 | 19.1 |
| P = 0.03 | P = 0.02 | |||||||
| Cigarette smoking | ||||||||
| Never | 103 | 25.4 | 282 | 56.5 | 29 | 1.9 | 397 | 24.6 |
| Former (quit >6 months ago) | 116 | 28.6 | 110 | 22.0 | 723 | 47.0 | 799 | 49.4 |
| Current | 187 | 46.1 | 107 | 21.4 | 785 | 51.1 | 420 | 26.0 |
| Unknown | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 | 1 | 0.1 |
| P < 0.001 | P < 0.001 | |||||||
| Cigarette pack-years (mean (SD)) | 24.3 (23.1) | 7.2 (13.5) | 50.9 (28.7) | 22.1 (23.2) | ||||
| P < 0.001 | P < 0.001 | |||||||
| Other cancer(s)c | ||||||||
| No | 336 | 82.8 | 448 | 89.8 | 1,306 | 85.0 | 1,473 | 91.1 |
| Yes | 70 | 17.2 | 51 | 10.2 | 231 | 15.0 | 144 | 8.9 |
| P = 0.002 | P < 0.001 | |||||||
| Lung cancer morphology | ||||||||
| Adenocarcinoma | 220 | 54.2 | 582 | 37.9 | ||||
| Squamous cell carcinoma | 45 | 11.1 | 459 | 29.9 | ||||
| Large cell carcinoma | 28 | 6.9 | 61 | 4.0 | ||||
| Non-small-cell carcinoma NOS | 34 | 8.4 | 142 | 9.2 | ||||
| Small cell carcinoma | 38 | 9.4 | 157 | 10.2 | ||||
| Other | 26 | 6.4 | 65 | 4.2 | ||||
| Not available | 15 | 3.7 | 71 | 4.6 | ||||
| P < 0.001 | ||||||||
Abbreviations: EAGLE, Environment And Genetics in Lung cancer Etiology; NOS, not otherwise specified; SD, standard deviation.
P values were derived from the chi-square test (categorical variables) or Student's t test (continuous variables).
Percentages may not add to 100.0 because of rounding.
Primary cancer(s) (previously or newly diagnosed) other than lung cancer.