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. 2005 Apr 30;20(2):283–290. doi: 10.3346/jkms.2005.20.2.283

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Copyright © 2005 The Korean Academy of Medical Sciences

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 6 — The histopathologic findings of skeletal muscle biopsy specimen in AD EDMD2 (A) and LGMD1B (B-D) patient. (A) Myofibers are reduced in number and replaced by fibroadipose tissues. There are atrophic or hypertrophic myofibers, internalization of sarcolemmal nuclei and fiber splitting (hematoxylin and eosin stain, ×200). (B) Variation in myofiber size, frequent internal nuclei and fatty ingrowth are noted in hematoxylin and eosin stain (×200). (C) ATPase pH 4.6 stain reveals atrophy of type 1 fibers (dark brown stain, ×200). (D) ATPase pH 9.4 stain reveals a predominance of type 2 fibers (brown stain, ×100).