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Photographs showing the morphological features of CCI-induced brain injury. The extent of contusion is greatest in the saline-treated group (A). The contusion volume in the saline-treated group, 100 mg-GTSs-treated group (B), 200 mg-GTSs-treated group (C) were 32.5±3.5 µL, 26.5±2.9 µL, and 19.5±2.7 µL respectively. The effect of GTSs on brain contusion was increased in a dose-dependent fashion. CCI, controlled cortical impact; GTSs, ginseng total saponins.
