Fig. 3.
Photomicrographs showing the ipsilateral (A, C, E, G) and contralateral (B, D, F, H) hippocampus of rats subjected to CCI injury; saline-treated group (A to D), and 200 mg-GTSs-treated group (E to H). In the saline-treated group, there was a significant neuronal loss in the CA2 and CA3 regions compared with the intact hippocampus. The treatment with GTSs significantly prevented CCI-induced neuronal loss in the ipsilateral CA2 and CA3 regions compared with saline-treated group. Original magnification ×40 (upper panels) and ×100 (lower panels). H&E. CA, cornu ammonis; CCI, controlled cortical impact.