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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Hypertension. 2009 Nov 30;55(1):180–188. doi: 10.1161/HYPERTENSIONAHA.109.143818

Figure 2. ET-1 augments PE-induced vasoconstriction.

Figure 2

ET-1 or PugNAc incubation for 24h increases vascular contraction to (A) PE and (B) 5-HT in rat thoracic rats aorta vs. vehicle (methanol; n=5). ET-1-infusion for 14 days increases (C) PE-induced in arteries from Wistar rats (n=5). Experimental values of contraction were calculated relative to the contractile response produced by KCl 120mM, which was taken as 100%. Results are presented as mean ± SEM in each experimental group. *, p<0.05 vs. vehicle (H2O) or control.