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. Author manuscript; available in PMC: 2011 Jan 15.
Published in final edited form as: Spine (Phila Pa 1976). 2010 Jan 15;35(2):162–168. doi: 10.1097/BRS.0b013e3181b7f1a7

Table 1. Candidate Genes Identified on Chromosome 17 within the Areas of Interest.

Candidate Gene Approximate Map
Position (Mb)*
Function
Lethal giant larvae homolog 1 (LLGL1) 18 Cytoskeletal protein, cell cycle control
Microfibular-associated protein 4 (MFAP4) 19.2 Protein metabolism and modification
Nitric oxide synthase 2A (NOS2A) 23 Synthase, electron transport
Slingshot 2 (SSH2) 25 Phosphatase, cell structure/motility
Solute carrier family 6 (SLC6A4) 25.5 Serotonin transporter, signal transduction, bone accrual regulation
Carboxypeptidase D (CPD) 25.7 Intracellular trafficking
Neurofibromin 1 (NF1) 26.4 Neuronal signaling molecule
*

From the www.genome.ucsc.edu website