Table 2. Model-Independent Linkage Analyses Results for Candidate Region on Chromosome 17.
Marker | Approximate Map Position (Mb)* | Initial Population (P value) | Autosomal-dominant Subgroup (P value) | Families with Males with Idiopathic Scoliosis Treated with Surgery | |
---|---|---|---|---|---|
Single-point (P value) | Multipoint (P value) | ||||
D17s1298 | 3.61 | 0.1513 | 0.0433† | 0.0372 | 0.0266 |
D17s974 | 0.6514 | 0.0911 | 0.4547 | 0.2103 | |
D17s1303 | 10.8 | 0.6973 | 0.037 | 0.0855 | 0.1575 |
D17s969§ | 11.79 | N/A¶ | 0.3981 | 0.0101 | 0.0976 |
D17s799§‡ | 13.11 | 0.4442 | 0.0084 | 0.1082 | 0.1634 |
D17s918§ | 15.1 | N/A | 0.0589 | 0.4122 | 0.2185 |
D17s2196 | 17.21 | 0.0387 | 0.0086 | 0.2076 | 0.2661 |
D17s689§ | 20.9 | N/A | 0.1018 | 0.7156 | 0.1904 |
D17s975 | 25.12 | 0.0276 | 0.0864 | 0.0003 | 0.1937 |
D17s1293 | 29.58 | 0.0841 | 0.0026 | 0.0475 | 0.1478 |
D17s784 | 75.41 | 0.4397 | 0.8057 | 0.0217 | 0.0028 |
D17s928 | 77.84 | 0.4111 | 0.4429 | 0.0099 | 0.0032 |
From the www.genome.ucsc.edu website
Boldface indicates statistically significant values (P ≤ 0.05)
Fine-mapping marker
N/A, not applicable.
Logarithm of odds score was 3.2024