Table 3. Model-Independent Linkage Results for SNPs on 17q11.2.

Marker	Position* (Mb)	Associated Gene	Familial Idiopathic Scoliosis Families with Males Treated with Surgery		Location
			Single-point (P value)	Multi-point (P value)
rs1472081	24.42	--†	0.01827§	0.19811	Unknown
rs8067041	24.5	MYO18A	0.31121	0.19735	Intron
rs6505114	24.52	MYO18A	0.63171	0.19713	Intron
rs894606	24.93	GIT1	0.65590	0.19514	Intron
rs3110492	24.95	--	0.02810	0.19506	Unknown
d17s975	25.12	SSH2	0.00037	0.19371	Intron
rs2467334	25.16	SSH2	0.18985	0.19349	Intron
rs4436830	25.41	EFCAB5	0.17881	0.18809	Intron
rs4325622	25.55	SLC6A4	0.00028	0.10264	Intron
rs2066713	25.58	SLC6A4	0.00241	0.09264	Intron
rs3816828	25.62	BLMH	0.46811	0.07718	Intron
rs7342921	25.64	BLMH	0.00409	0.00945	Exon
rs3794794	25.74	CPD	0.09817	0.07765	Intron
rs2191351	25.78	CPD	0.05990	0.07954	Intron
rs170053	25.92	--	0.07734	0.08812	Unknown
rs2905787	26.51	NF1	0.36028	0.16494	Intron
rs2057769	26.72	NF1	0.42398	0.20561	Intron
rs2107359	26.72	NF1	0.68507	0.20578	Intron
rs2074153	26.88	Rab11-FIP4	0.00331	0.20277	Intron
rs739630	26.9	--	0.03891	0.20302	Unknown
rs886224	27.25	--	0.79680	0.21401	Intron
rs753750	27.64	RHBDL3	0.05750	0.23211	Intron

Genes: MYO18A = myosin 18A isoform b, GIT1 = G protein-coupled receptor kinase interactor 1, SSH2 = Protein phosphatase Slingshot homolog 2, EFCAB5 = EF-hand calcium binding domain 5, SLC6A4 = solute carrier family 6 member 4, BLMH = Bleomycin hydrolase, CPD = carboxypeptidase D precursor, NF1 = neurofibromin isoform 1, Rab11-FIP4 = Rab11 family interacting protein 4, RHBDL3 = rhomboid, veinlet-like 3

^*From www.genome.ucsc.edu

^†No gene association.

^§Boldface indicates statistically significant values (P ≤ 0.05)