TABLE 1. Body composition.

Fat and lean mass and fractional fat content of Lep^ob, Lepr^db, Cpe^fat, tub, and +/+ (C57BL/6J) mice measured by TD-NMR. Body composition data for the Diet Induced Obese (DIO) mice and their controls were obtained from The Jackson Laboratory (Maine, USA; personal communication).

Mouse (N=5)	Age (weeks)	Body Weight (g) [SD]	Fat (g) [SD]	Lean mass (g) [SD]	% fat [SD]
Lepob	4	24.2 [0.9]	9.4 [0.8]	13.1 [0.3]	39 [2.1]
Leprdb	4	24.5 [2.2]	8.5 [1.3]	14.1 [0.8]	35 [2.7]
tub	4	27.0 [0.8]	2.8 [0.3]	22.8 [0.9]	10 [1.2]
Cpefat	4	20.5 [1.9]	2.8 [0.5]	17.2 [2.1]	13 [1.4]
+/+	4	18.0 [1.3]	2.1 [0.5]	16.6 [1.5]	11 [0.9]
DIO	18	37.0 [2.9]	12.9 [0.91]	21.1 [1.7]	35 [2.4]
DIO control	18	30.0 [2.0]	7.0 [0.7]	2.01 [1.0]	23 [2.2]

Values are mean ± SD