Table 2. Statistical analyses of body mass and composition measurements.
ANOVA for body mass and body composition by genotype at Lepr 223 in mice fed HF or LF diets up to day 190. Area Under the Curve from data points taken every week was calculated for each mouse and grouped by (A) sex, diet and genotype (up to day 190), or (B) sex and diet (up to day 120).
| Days 21-190 | MALE | DIFFERENCE | MALE | DIFFERENCE | FEMALE | DIFFERENCE | FEMALE | DIFFERENCE | |
|---|---|---|---|---|---|---|---|---|---|
| A | DEPENDENT VARIABLE | HF: Q/Q, Q/R, R/R | LF: Q/Q, Q/R, R/R | HF: Q/Q, Q/R, R/R | LF: Q/Q, Q/R, R/R | ||||
| BODY WEIGHT | F=0.69, df=2,48, p =0.52 | - | F=0.42, df=2,63, p =0.66 | - | F=1.61, df=2,36, p = 0.24 | - | F=0.94, df=2,64, p = 0.41 | - | |
| FAT MASS | F=1.92, df=2,48, p =0.19 | - | F=0.33, df=2,63, p =0.71 | - | F=2.49, df=2,36, p = 0.13 | - | F=0.31, df=2,64, p = 0.73 | - | |
| LEAN MASS | F=1.81, df=2,48, p =0.21 | - | F=0.09, df=2,63, p =0.90 | - | F=0.03, df=2,36, p = 0.97 | - | F=2.66, df=2,64, p = 0.10 | - | |
| % FAT | F=2.47, df=2,48, p =0.13 | - | F=0.37, df=2,63, p =0.69 | - | F=2.06, df=2,36, p = 0.17 | - | F=0.24, df=2,64, p = 0.78 | - | |
| Days 21-120 | |||||||||
| B | DEPENDENT VARIABLE | HF, LF | HF versus LF | HF, LF | HF versus LF | ||||
| BODY WEIGHT | F=6.40, df=1,115, p =0.07 | - | F=8.10, df=1,104, p =0.06 | - | |||||
| FAT MASS | F=17.61, df=1,115, p =0.0002 | +50% | F=49.27, df=1,104, p <0.0001 | +54% | |||||
| LEAN MASS | F=185.51, df=1,115, p <0.0001 | -27% | F=116.56, df=1,104, p <0.0001 | -27% | |||||
| % FAT | F=17.35, df=1,115, p =0.0003 | +30% | F=55.65, df=1,104, p <0.001 | +50% | |||||