FIGURE 2.

Adjusted mean change from baseline to endpoint in HAMD₁₇ total score, anxiety/somatization and core mood. ^ap-values for adjusted mean differences [HAMD₁₇ total score=0.41, 95% CI (-1.69, 2.51); Anxiety/somatization subscore=0.28, 95% CI (-0.59, 1.16); Core mood subscore=0.36, 95% CI (-0.47, 1.19)] using Type III Sums Of Squares from analysis of covariance (ANCOVA) model: change=PPS group, propensity score and baseline. ^*Within group p-value (p<0.001) from ANCOVA model: change=PPS group, propensity score and baseline, and is the same for HAMD₁₇ total score and both subscores that are presented here. PPS+: painful physical symptom positive group, PPS-: remainder of study population, HAMD₁₇: 17-item Hamilton Depression Rating Scale, CI: confidence interval.