Figure 2.

New Pfam display of a protein domain architecture. Pfam-A families classified as type ‘family’ and ‘domain’ with a lozenge shape, and families with type ‘repeat’ or ‘motif’ are represented by rectangles. The alignment co-ordinates are depitcted with a solid colour, and the envelope co-ordianates in a lighter shade of this colour. Where the profile HMM match for a domain or family is only of partial length, the curved end of the lozenge/rectangle is replaced by a jagged edge. Active-site residues are marked with a lollipop with a diamond-shaped head. An example tooltip showing the domain description, co-ordinates and source is shown for the fourth domain. Note the overlapping envelopes between fourth and fifth domains.