Table 2.

KEGG MEDICUS for disease and drug information

	KEGG DISEASE	KEGG DRUG
URL	http://www.genome.jp/kegg/disease/	http://www.genome.jp/kegg/drug/
Database	Gene/molecule lists consisting of disease genes, environmental factors, diagnostic markers, and therapeutic drugs	Chemical structures and/or components of approved drugs in Japan, United States and Europe with additional information including: targets, metabolizing enzymes and drug interactions
Pathway map	KEGG pathway maps for human diseases including: cancers, immune disorders, neurodegenerative diseases, circulatory diseases, metabolic disorders and infectious diseases	KEGG pathway maps for drug metabolism; KEGG pathway maps for biosynthesis of antibiotics and natural products; and KEGG DRUG structure maps for drug development
BRITE hierarchy	Disease classifications including: Pathogens and infectious diseases; Human diseases; and ICD-10 disease classification	Drug classifications including: Therapeutic category of drugs (Japan); ATC classification (WHO); TCM (Traditional Chinese Medicine) drugs in Japan; and Crude drugs in Japan
Release	2008	2005