Table 1.
Correlation between RASSF1A promoter methylation and clinicopathological index in NPC
| No. of patient | Promoter methylation status | Frequency of methylationincidence | |||
|---|---|---|---|---|---|
| Methylated | Unmethylated | ||||
| Gender | NS | ||||
| Male | 22 | 17 | 5 | 77.27% | |
| Female | 16 | 10 | 6 | 62.50% | |
| Age | NS | ||||
| ≤50 | 17 | 14 | 3 | 82.35% | |
| >50 | 21 | 13 | 8 | 61.90% | |
| Histological subtype | p = 0.047 | ||||
| poorly differentiated | 27 | 22 | 5 | 81.48% | |
| Well-differentiated | 11 | 5 | 6 | 45.45% | |
| Stage | NS | ||||
| I and II | 13 | 9 | 4 | 69.23% | |
| III and IV | 25 | 18 | 7 | 72.00% | |
| Lymph node | NS | ||||
| Positive | 29 | 22 | 7 | 75.86% | |
| Negative | 9 | 5 | 4 | 55.56% | |
| Distance metastasis | NS | ||||
| Positive | 5 | 4 | 1 | 80.00% | |
| Negative | 33 | 23 | 10 | 69.70% | |