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. 2009 Nov 26;65(2):275–284. doi: 10.1093/jac/dkp421

Table 2.

Suppression of IFV-induced apoptosis in HAE by DAS181

Fold change in gene expression
Apoptosis gene PBS treated DAS181 treated
BIK 13.7 1.1
BAG4 −475.0 −1.4
TNFRSF11b −898.9 −1.2

PBS or DAS181 (7.5 µg/cm2) was incubated with HAE tissues for 2 h immediately prior to IFV B/Maryland/1/59 infection (10 000 pfu/well). Cellular RNA was later extracted and assayed for apoptosis gene expression. Fold changes of gene expression, from untreated HAE culture, are shown for the genes with changes ≥2.0-fold.