Table 2.

Endothelial parameters in PCOS patients treated with metformin plus supplementation with folate (experimental group) or metformin plus placebo (control group) at study entry and after 6 months of treatment

	Experimental (n = 23)		Control (n = 24)
	Baseline	6 Months	Baseline	6 Months
BAD-B (mm)	3.4 ± 0.5	2.8 ± 0.6*	3.5 ± 0.6	3.0 ± 0.5*†
BAD-RH (mm)	3.7 ± 0.4	3.4 ± 0.6*	3.7 ± 0.3	3.6 ± 0.7*†
FMD (%)	14.4 ± 1.9	16.2 ± 2.1*	14.4 ± 2.0	15.3 ± 1.8*†
IMT (mm)	0.53 ± 0.09	0.39 ± 0.08*	0.55 ± 0.11	0.50 ± 0.07*†
ET-1	1.1 ± 0.4	0.7 ± 0.5*	1.2 ± 0.6	0.9 ± 0.5*†

Data are means ± SD.

*P < 0.05 vs. baseline.

†P < 0.05 vs. experimental group.