Table 1.
Crude, directly standardized mortality rates (per 1,000 person-years) and SMRs by sex and diabetes in patients with cystic fibrosis
| Patients (n) | Person-years at risk | Deaths (n) | Crude mortality rate (95% CI) | Directly standardized mortality rate (95% CI)* | SMR (95% CI)* | |
|---|---|---|---|---|---|---|
| Total | 5,892 | 17,672 | 393 | 22.2 (20.1–24.6) | 26.8 (19.0–40.5) | 55.5 (40.8–70.1) |
| Male | 3,155 | 9,425 | 191 | 20.3 (17.6–23.4) | 23.5 (14.9–43.3) | 39.8 (24.7–55.0) |
| Female | 2,737 | 8,247 | 202 | 24.5 (21.3–28.1) | 30.9 (19.0–56.5) | 84.1 (53.4–114.7) |
| Diabetes | 696 | 1,953 | 141 | 72.2 (61.2–85.1) | 48.4 (27.7–106.2) | 123.4 (74.7–172.1) |
| Male | 349 | 970 | 61 | 62.9 (48.9–80.8) | 41.9 (22.2–106.8) | 82.2 (33.6–130.9) |
| Female | 347 | 983 | 80 | 81.4 (65.4–101.3) | 56.1 (24.0–209.8) | 208.7 (99.4–318.0) |
| Without diabetes | 5,196 | 15,718 | 252 | 16.0 (14.2–18.1) | 20.6 (13.3–35.7) | 42.4 (28.1–56.7) |
| Male | 2,806 | 8,454 | 130 | 15.4 (12.9–18.3) | 16.7 (9.5–41.4) | 32.1 (16.9–47.2) |
| Female | 2,390 | 7,264 | 122 | 16.8 (14.1–20.1) | 25.4 (13.9–53.9) | 60.4 (31.3–89.5) |
*Using the 2005 population of England and Wales as a standard population.