Table 3.
Independent determinants of time to CVD and all-cause mortality in FDS primary prevention subjects aged ≥65 years
| HR (95% CI) | P value | |
|---|---|---|
| Cardiovascular mortality | ||
| Age (increase of 10 years) | 2.98 (1.76–5.04) | <0.001 |
| Alcohol consumption | 1.09 (1.01–1.17) | 0.024 |
| BMI (increase of 1 kg/m2) | 0.91 (0.85–0.97) | 0.004 |
| Diabetes duration (increase of 5 years) | 1.28 (1.09–1.50) | 0.002 |
| Regular aspirin use | 0.35 (0.11–1.13) | 0.079 |
| All-cause mortality | ||
| Age (increase of 10 years) | 2.69 (1.83–3.95) | <0.001 |
| BMI (increase of 1 kg/m2) | 0.93 (0.89–0.97) | 0.002 |
| Diastolic blood pressure (increase of 1 mmHg) | 0.98 (0.97–1.00) | 0.050 |
| Any exercise | 0.59 (0.39–0.91) | 0.016 |
| Insulin therapy | 1.87 (1.05–3.32) | 0.033 |
| ln(urinary ACR)* | 1.26 (1.10–1.45) | 0.001 |
| Male sex | 1.84 (1.22–2.78) | 0.004 |
| Southern European ethnicity | 0.37 (0.20–0.68) | 0.001 |
| Regular aspirin use | 0.40 (0.19–0.84) | 0.015 |
The most parsimonious models are shown with HRs (95% CI). The HRs for regular aspirin use are those after adjustment for the significant variables in the models.
*A 2.72-fold increase in ACR or triglycerides corresponds to an increase of 1 in ln(ACR).