Table 2.
Effects of glyphosate treatment on mitotic index and micronuclei induction in swiss albino mice.
Groups (treatment) | Mitotic index (MI) after treatment | Micronuclei induction (MNPCEs/1000PCEs) after treatment | ||||
---|---|---|---|---|---|---|
24 hours | 48 hours | 72 hours | 24 hours | 48 hours | 72 hours | |
Group I | 4.88 ± 0.06 | 4.90 ± 0.02 | 4.84 ± 0.04 | 1.24 ± 0.01 | 1.10 ± 0.01 | 1.18 ± 0.03 |
(untreated) | ||||||
Group II B(a)P | 2.46 ± 0.09# | 2.12 ± 0.01# | 1.94 ± 0.02# | 15.46 ± 0.03* | 17.50 ± 0.10* | 18.25 ± 0.12* |
(100 mg/kg b.wt) | ||||||
Group III (glyphosate | 4.12 ± .05# | 3.84 ± 0.04# | 3.75 ± 0.03# | 3.87 ± 0.02* | 5.76 ± 0.08* | 6.12 ± 0.07* |
dose 25 mg/kg b.wt) | ||||||
Group IV (glyphosate | 3.54 ± 0.01# | 3.16 ± 0.03# | 3.06 ± 0.01# | 6.86 ± 0.04* | 8.25 ± 0.04* | 8.48 ± 0.09* |
dose 50 mg/kg b.wt) |
Data shows mean ± SE of 5 animals in each group.
# P < .05 represents significant decrease as compared to untreated control.
*P < .05 represents significant increase as compared to untreated control.
MNPCEs: Micronucleated polychromatic erythrocytes;
PCEs: Polychromatic erythrocytes.