Table 6.
Regression analyses of initial ados subscales versus urinary metal excretion and initial glutathione. In the regression equation, the suffixes for the metals refer to the value at Baseline (B) and after the 9th ( 9) dose of DMSA in Phase 1.
| Adjusted R 2 | P-value | Equation | Most significant variables | |
|---|---|---|---|---|
| ADOS-Sociability | 0.41 | 0.004 | 8.70 + 1.20 PbB + 0.217 SnB + 12.7 TlB − 1.64 HgB − 10.2 SbB − 2.61 CdB − 0.631 AlB − 0.186 Pb9 − 7.13 Tl9 + 6.27 Sb9 +6.15 W9 +3.62 Cd9 | W9***, AlB**, TlB*, HgB*, Pb9*, Tl9* |
| ADOS-Commun. | 0.37 | 0.0003 | 2.39–2.57 HgB + 23.1 SbB + 2.32 Hg9 + .0048 Glut | HgB**, Hg9**, SbB** |
| ADOS-Play | 0.24 | 0.004 | 1.20 + 0.540 PbB + 4.23 Sb9 + 0.0017 Glut | PbB* |
| ADOS-SBRI | 0.21 | 0.02 | 4.64–0.897 HgB − 2.63 CdB − 0.26 AlB + 0.050 Pb9 + 0.730 Hg9 |
***P < .001, **P < .01, *P < .05