Table 6.
Effect of SE5-OH administration on the F1 generation rat dam reproductive performance.
| Dose (mg/kg/day) | Mean estrus cycle | Incidence of irregular estrus cycle | Mating period | Copulation index (%)A | Fertility index (%)B | |
|---|---|---|---|---|---|---|
| Number of estrus | Day of conceiving | |||||
| 0 | 4.36 ± 0.46# | 0.1 ± 0.6 | 3.1 ± 2.8 | 95.5 | 85.7 | |
| (n = 24) | 0/24 | (n = 22) | (n = 21) | (21/22) | (18/21) | |
| 200 | 4.31 ± 0.45 | 0.2 ± 0.7 | 2.8 ± 1.8 | 95.7 | 86.4 | |
| (n = 21) | 2/23 | (n = 23) | (n = 22) | (22/23) | (19/22) | |
| 1000 | 4.39 ± 0.41 | 0.1 ± 0.2 | 2.3 ± 1.3 | 100.0 | 95.0 | |
| (n = 20) | 0/20 | (n = 20) | (n = 20) | (20/20) | (19/20) | |
| 2000 | 4.30 ± 0.43 | 0.0 ± 0.0 | 2.5 ± 1.5 | 100.0 | 95.5 | |
| (n = 21) | 1/22 | (n = 22) | (n = 22) | (22/22) | (21/22) | |
#Mean ± standard deviation; Anumber of copulated females/number of pairs; Bnumber of pregnant females/number of copulated females; n: number of mating pairs.