FIG. 4.

Gene expression on aligned and unaligned scaffolds over time. (A) Fibroblast expression of glyceraldehyde-3-phosphate dehydrogenase (GAPDH), integrins, and type I and type III collagen. (B) Expression of the α2 integrin differed significantly on the aligned and unaligned scaffolds at all time points examined (*p < 0.05). (C) Expression of αV was significantly higher on the unaligned scaffolds at day 14 (*p < 0.05). (D) Although β1 expression did not vary significantly between the two scaffold types, it increased significantly over time (*p < 0.05). Color images available online at www.liebertonline.com/ten.