Skip to main content
. Author manuscript; available in PMC: 2010 Oct 2.
Published in final edited form as: J Mol Biol. 2009 Aug 6;392(4):1102–1115. doi: 10.1016/j.jmb.2009.07.093

Figure 1.

Figure 1

The crystal structure of the β2AR-carazolol complex structure. Left: the β2AR receptor is represented by cartoon and the seven transmembrane helices are labeled. Carazolol is represented by van der Waals spheres. Residues Asp192 and Phe193 of ECL2, and Lys305 and Tyr308 of TM7 are represented by stick and in different colors. The salt bridge between Asp192 and Lys305 is represented by dash line, which partially covers the extracellular opening and divides it into two small areas. Right: carazolol formed close interactions with several polar transmembrane residues D113 (TM3), N312 (TM7), Y316(TM7), S203(TM5) and S207(TM5). Hydrogen bonds are represented by dash lines.