Skip to main content
. 2010 Jan 22;6(1):e1000819. doi: 10.1371/journal.pgen.1000819

Figure 2. Intron gain in response to low complexity sequence in the gene CG42594.

Figure 2

While the exact sequence of this highly variable region in the common ancestor of D. melanogaster and D. ananassae is not known, it is plausible that a single nucleotide deletion within the QSGQSG amino acid repeat (blue shading) generated the canonical 5′ splice site CAG | GTGAGT used by this phase 0 intron. Similarly, the CAG repeat (encoding poly-Q sequence) is a potent 3′ splice acceptor site [45]. Sequence conservation across all species is indicated with light shading. The novel intron (denoted by < >) is highly length variable across all species of the melanogaster group.