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. 2010 Jan 22;6(1):e1000828. doi: 10.1371/journal.pgen.1000828

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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Colony survival assay of asynchronous populations of cells exposed to (A) camptothecin (CPT), (B) etoposide (VP16), (C) ICRF-193, and (D) methyl methanesulfonate (MMS). The dose is displayed on the X axis on a linear scale, while the percent fraction of surviving colonies is displayed on the Y axis on a logarithmic scale. To count the surviving colonies, cells were grown for 8–10 days in methylcellulose medium containing various concentrations of DNA–damaging agents. At least three independent experiments were performed with triplicate samples, and the representative results are shown. The error bars indicate S.D.