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. Author manuscript; available in PMC: 2010 Jul 21.
Published in final edited form as: Oncogene. 2009 Oct 19;29(3):380–391. doi: 10.1038/onc.2009.336

Figure 3. Rheb subcellular localization is dependent on Rce1- and Icmt-catalyzed modifications.

Figure 3

(a) Rce1 +/+, Rce1 −/−, Icmt +/+, and Icmt −/− MEFs were transiently transfected with pEGFP vector or with pEGFP encoding GFP-tagged Rheb1 (F-Rheb1), Rheb1 M184L (GG-Rheb1), Rheb2 (F-Rheb2), or Rheb2 M183L (GG-Rheb2). Live cells were imaged by confocal microscopy. (b) Quantification of the data shown in (a). At least 30 cells in each condition were scored.