Table 2.
Apolipoprotein concentrations, mg/dl, in Apo E (−/−) and Apo E (−/−)+ hepatic lipase (−/−) mice
| Fraction | Apo E (−/−)
|
Apo E (−/−)+ hepatic lipase (−/−)
|
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| B-100 | B-48 | A-IV | A-I | A-II+Cs | B-100 | B-48 | A-IV | A-I | A-II+Cs | |
| Females | ||||||||||
| Total | 2.9 | 28.5 | 7.3 | 21.3 | 29.8 | 5.0 | 39.6 | 35.4 | 103.8 | 92.5 |
| VLDL | 0.6 | 13.5 | 5.2 | 5.5 | 17.8 | 0.9 | 9.9 | 10.3 | 3.1 | 14.7 |
| IDL | 0.7 | 6.7 | 1.1 | 4.5 | 4.6 | 0.9 | 9.0 | 7.3 | 4.1 | 7.7 |
| LDL | 1.6 | 6.6 | 0.3 | 3.6 | 1.6 | 2.7 | 14.9 | 9.9 | 8.3 | 9.4 |
| HDLL | — | 1.7 | 0.1 | 0.3 | 0.9 | 0.5 | 3.9 | 5.3 | 5.8 | 3.8 |
| HDLH | — | — | 0.6 | 7.4 | 4.9 | — | 1.9 | 2.6 | 82.5 | 56.9 |
| Males | ||||||||||
| Total | 6.1 | 54.2 | 45.6 | 95.7 | 158.5 | |||||
| VLDL | 4.0 | 26.7 | 8.0 | 11.3 | 34.9 | 2.1 | 24.7 | 21.0 | 8.1 | 49.4 |
| IDL | 0.7 | 6.8 | 1.0 | 4.2 | 3.6 | 1.1 | 10.2 | 8.0 | 5.0 | 11.4 |
| LDL | 2.7 | 13.9 | 9.8 | 9.0 | 11.9 | |||||
| HDLL | 0.2 | 3.9 | 4.3 | 7.3 | 7.6 | |||||
| HDLH | — | 1.5 | 2.5 | 66.3 | 78.2 | |||||
Data from Apo E (−/−) mice are from single pools of plasma from eight males and four females; data from Apo E (−/−)+ hepatic lipase (−/−) mice are means from two pools of seven to ten mice each.