Table 3.
Composition of lipoprotein species in Apo E (−/−)+ hepatic lipase (−/−)+ Apo E (−/−) mice
| Component | IDL, % mass
|
LDL, % mass
|
||||
|---|---|---|---|---|---|---|
| Double deficiency
|
Apo E (−/−) | Double deficiency
|
Apo E (−/−) | |||
| Lamellar | Spherical | Lamellar | Spherical | |||
| CE | 11.0 | 46.8 | 40.8 | 12.4 | 28.3 | 35.7 |
| TG | 4.1 | 1.9 | 7.7 | 1.4 | 2.3 | 5.4 |
| FC | 28.5 | 10.3 | 15.7 | 28.3 | 11.3 | 16.8 |
| PL | 50.0 | 30.2 | 23.8 | 52.6 | 43.7 | 26.6 |
| Protein | 6.3 | 10.6 | 12.1 | 5.1 | 14.1 | 15.6 |
| B-100 | 0.2 | 0.1 | 0.5 | 0.1 | 0.6 | 1.8 |
| B-48 | 2.2 | 3.1 | 4.9 | 1.5 | 4.9 | 7.5 |
| A-IV | 2.4 | 1.2 | 0.7 | 2.5 | 1.5 | 0.3 |
| A-I | — | 2.9 | 3.1 | 0.5 | 5.9 | 4.1 |
| A-II + Cs | 1.5 | 3.3 | 2.9 | 0.5 | 1.2 | 1.9 |
CE, cholesteryl esters; TG, triglycerides; FC, free cholesterol; PL, phospholipids.