Skip to main content
. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Expert Opin Biol Ther. 2010 Feb;10(2):163–178. doi: 10.1517/14712590903431022

Table 3. Current Pediatric Clinical Trials: Tumor Vaccines.

Clinical trial number Title Primary Site / Sponsor
NCT00526240 A Pilot Study of Tumor Vaccination in Patients With Neuroblastoma and Pediatric Sarcomas and Altered T-Cell Homeostasis National Cancer Institute
NCT00058799 Phase I CD40 Ligand & IL-2 gene modified leukemia vaccine Baylor College of Medicine
NCT00048386 Phase I/II IL-2 gene modified autologous neuroblastoma vaccine Baylor College of Medicine
NCT00703222 Phase I/II post autologous HSCT Baylor College of Medicine
NCT00002748 Phase I IL-2 gene modified autologous or partially matched allogeneic neuroblastoma vaccine St. Jude Children's Research Hospital
NCT00186862 Phase I Lymphotactin and IL-2 gene modified neuroblastoma vaccine post chemotherapy St. Jude Children's Research Hospital
NCT00258687 Phase I Vaccination with GM-CSF gene modified, autologous, lethally irradiated clear cell sarcoma, alveolar soft part sarcoma, renal cell carcinoma or melanoma vaccine Dana-Farber Cancer Institute
NCT00069940 Phase I Vaccination with telomerase peptide + GM-CSF for brain tumors, GIST and sarcomas Dana-Farber Cancer Institute
NCT00085397 Randomized Phase II Immunization against melanoma comparing autologous dendritic cells pulsed with gp100 peptide to autologous dendritic cells fused with autologous tumor cells Dana-Farber Cancer Institute
NCT00576641 Phase l Tumor-associated antigen pulsed dendritic cell vaccine for brain stem glioma and glioblastoma Cedars-Sinai Medical Center
NCT00576537 Phase ll Tumor lysate-pulsed dendritic cell vaccine for brain tumors Cedars-Sinai Medical Center
NCT00101309 Phase I EBV-transformed fusion tumor cell vaccine for relapsed Ewing's sarcoma and neuroblastoma Milton S. Hershey Medical Center
NCT00107185 Phase I Dose escalation study of autologous tumor lysate-pulsed dendritic cell vaccine for malignant gliomas Jonsson Comprehensive Cancer Center
NCT00405327 Phase II Tumor lysate-pulsed dendritic cell vaccine for high-risk solid tumor patients following autologous HSCT University of Michigan Cancer Center