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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Mol Cell Biochem. 2009 Sep 13;335(1-2):107–118. doi: 10.1007/s11010-009-0247-6

Fig. 1. Analysis of MnSOD protein, activity, and mRNA expression levels in human breast cancer cell lines.

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A. Average MnSOD protein levels by genotype. Each point represents the average MnSOD expression for each cell line (n=3) and the bar is the average of all three cell lines. The ala/ala cell lines analyzed as a group had significantly more MnSOD protein expression that the val/val cell lines (p<0.05). B. MnSOD protein expression in individual cell lines (*MCF7 and T47D are significantly different from ZR75-1, p<0.01). C. MnSOD protein adjusted for mitochondrial density represented by porin protein levels (*p<0.05 versus MCF-7 and T47D). D. MnSOD enzymatic activity (*p<0.05 versus MCF-7, T47D, ZR-75-30, and MDA-MB-231, **p<0.05 versus ZR-75-30). E. MnSOD protein corrected for MnSOD mRNA expression (p=0.08). All experiments were completed in triplicate (n=3 ± SD)