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VMH NOS inhibition impairs the CRR to hypoglycemia. Blood glucose level (A); GIR (B); plasma epinephrine (C), and glucagon levels (D) during hyperinsulinemic/hypoglycemic clamp (1.2 units · kg−1 · h−1) of animals injected bilaterally in the ventromedial hypothalamus with aCSF (controls; n = 8) or l-NMMA (50 mmol/l; n = 6). *P < 0.05 vs. controls (two-way ANOVA).
