Table 2.
Comparison of Antiseptic Products
| OR Durability | Incidence of Surgical Site Infection | Ease of Use | |||||
| Antiseptic | Soak | Drape lift | General | General | Cardiac | Application | Cost |
| Stahl et al9 N = 36 P = .006 | Jacobson et al10 N = 171 P < .0001 | Pinheiro et al11 N = 214 P < .05 | Swenson et al12 N = 3209*P < .002 | Segal and Anderson13 N = 209 P = .02 | Armstrong et al17 N = 25 | Roberts et al18 N = 200 P = .0001 | |
| DuraPrep solution† | 3.7 bacterial log reduction | 1.5 cm2 | 4.8% | 3.9% | 4% | 82.8 sec With drape application | $56.96 |
| Tincture of iodine | – | – | 14.7% | – | – | – | |
| Prevail‡ | – | – | – | – | 42.2 sec | – | |
| ChloraPrep§ | 3.2 bacterial log reduction | – | – | 7.1% | – | – | – |
| PVP-I | – | 9.9 cm2 | – | 6.4% | 13% | 228 sec | $135.28 |
OR, operating room; PVP-I, povidone-iodine.
*
Number of procedures.
†
DuraPrep™ solution is from 3M Health Care (St. Paul, MN).
‡
Prevail-FX® is from Cardinal Health (Dublin, OH).
§
ChloraPrep® is from CareFusion, Inc. (Leawood, KS).
Adapted with permission from Roberts AJ et al.18