Table 1.
Domain | Solifenacin 5 mg* | Solifenacin 10 mg* | Tolterodine ER 4 mg† | Tolterodine 2 mg‡ | Oxybutynin 2.5/5 mg‡ | Darifenacin 7.5/15 mg‡ | Fesoterodine 4 mg† | Fesoterodine 8 mg§ | Oxybutynin Transdermal‡ |
General health | −4.3 | −4.0 | −1.9 | −0.45 | 0.58 | 0.15 | −2.9 | −2.6 | −1.2 |
Incontinence impact | −24.7 | −27.3 | −22.7 | −10.38 | −8.62 | −19.42 | −7.8 | −9.6 | −13.5 |
Role limitations | −20.6 | −22.7 | −21.5 | −11.44 | −9.07 | −21.30 | −18.5 | −21.4 | −13.3 |
Physical limitations | −17.7 | −20.3 | −18.8 | −8.23 | −8.01 | −17.79 | −17.2 | −19.6 | −11.7 |
Social limitation | −11.3 | −11.7 | −13.2 | −6.16 | −6.77 | −10.62 | −11.6 | −13.8 | −6.7 |
Personal relationships | −8.7 | −9.3 | −10.0 | −2.78 | −5.0 | −5.41 | −7.8 | −9.6 | −6 |
Emotions | −16.0 | −17.7 | −14.2 | −4.57 | −6.51 | −11.75 | −12.4 | −15.3 | −8.8 |
Sleep/energy | −13.8 | −14.4 | −12.7 | −5.98 | −6.15 | −8.10 | −10.7 | −12.3 | −11.2 |
Severity(coping) measure | −10.5 | −13.2 | −12.4 | −6.16 | −5.48 | −8.77 | −11.3 | −13.7 | −8.6 |
ER, extended release.
P < .001 compared with placebo.
P < .01 compared with placebo.
P < .001 compared with baseline.
P < .05 compared with placebo.