TABLE 3.

ROBUSTNESS PARAMETERS

Parameter	Variation	Effect on chromatogram
		Cefpodoxime proxetil		Clavulanicacid
		Normal RT	After variation	Normal RT	After variation
Ratio of mobile phase
	72:28	6.4	6.3	4.4	4.3
	68:32	6.4	6.4	4.4	4.5
Peak shape		sharp	sharp	sharp	sharp
Flow rate	1.2 ml	6.4	5.6	4.4	3.7
	0.8 ml	6.4	7.0	4.4	5.5
Peak shape		sharp	sharp	sharp	sharp
pH	3.2	6.4	6.2	4.4	4.2
	2.8	6.4	6.4	4.4	4.5
Peak Shape		sharp	sharp	sharp	sharp

RT = Retention time