(A) GSEA profiles of the sets of H3K27me3 target genes, NP-high (enriched in neuronal progenitors) and ME-high genes (enriched in mesoendodermal lineage).
(B) Heatmaps show expression of genes in three gene sets indicated in (A) in Jmjfl/fl and Jmj−/− cells during ESC differentiation.
(C) Time-course analysis of marker genes during differentiation by RT-qPCR. Error bars are standard deviations of relative expression shown in the y-axis.