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. Author manuscript; available in PMC: 2010 Jan 22.
Published in final edited form as: J Med Chem. 2009 Feb 26;52(4):952–963. doi: 10.1021/jm8008103

Table 2.

Sulfides

Sulfides Biological Data
Compound Structure KASIII IC50 (μM) P.f. W2 IC50 (μM) P.f. D6 IC50 (μM)
1a graphic file with name nihms164354t1.jpg 2.8 4.7 5.2
1b graphic file with name nihms164354t2.jpg 3.1 21.5 20.5
1c graphic file with name nihms164354t3.jpg 10.8 >49.9 >49.9
1d graphic file with name nihms164354t4.jpg 0.65 6.7 5.0
1e graphic file with name nihms164354t5.jpg 1.9 15.0 14.9
1f graphic file with name nihms164354t6.jpg 0.14 12.0 12.4
1g graphic file with name nihms164354t7.jpg 0.24 5.5 3.9
1h graphic file with name nihms164354t8.jpg 0.13 6.6 7.2
1i graphic file with name nihms164354t9.jpg 1.4 1.4 1.5
1j graphic file with name nihms164354t10.jpg 0.63 2.1 2.5
1k graphic file with name nihms164354t11.jpg 0.53 1.4 2.3