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. Author manuscript; available in PMC: 2010 Jan 22.
Published in final edited form as: J Med Chem. 2009 Feb 26;52(4):952–963. doi: 10.1021/jm8008103

Table 3.

Sulfonamides

Sulfonamides Biological Data
Compound Structure KASIII IC50 (μM) P.f. W2 IC50 (μM) P.f. D6 IC50 (μM)
2a graphic file with name nihms164354t12.jpg 50 >12.7 >12.7
2b graphic file with name nihms164354t13.jpg 195.2 >49.9 >49.9
2c graphic file with name nihms164354t14.jpg >1mM 6.1 0.04
2d graphic file with name nihms164354t15.jpg 2.2 >49.9 >49.9
2e graphic file with name nihms164354t16.jpg >1mM >49.9 >49.9
2f graphic file with name nihms164354t17.jpg 5.2 11.4 10.3
2g graphic file with name nihms164354t18.jpg 0.28 16.4 15.4