Table 3.
Profile of cellular recruitment of the treatments with caulerpin. Caulerpin (100 μmol/kg, p.o.) and indomethacin (100 μmol/kg, p.o.) were used in the carrageenan-induced (2.5 mg/animal) peritoneal inflammation test. The cell number were determinated by optical microscopic.
| Treatment |
Percentage of cells (%) |
|||
|---|---|---|---|---|
| Polymorphonuclear | Lymphocyte | Monocyte | Basophil | |
| Saline | 15.5 | 80.0* | 1.5 | 3.0 |
| Carrageenan | 34.5 | 44.0 | 20.5 | 1.0 |
| Indomethacin + Carrageenan | 7.0* | 68.0* | 21.0 | 4.0 |
| Caulerpin + Carrageenan | 6.0* | 63.0* | 31.0* | 0.0 |
Each point represents the % of inhibition of the cell number versus positive control (carrageenan) of six animals. Statistical differences between the treated and the control groups were evaluated by ANOVA and Dunnett tests and the asterisks denote the significance levels in comparison with control groups,
*
P < 0.05,
**
P < 0.01.