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Pfnek-1 inhibitory and P. falciparum activities of compounds 1–6, 8, 12–13 (IC50 values are in μM).
| Compound number | Pfnek-1 | FCB1 of P. falciparum |
|---|---|---|
| 1 | >50 | >100 |
| 2 | >50 | >100 |
| 3 | >50 | >100 |
| 4a | 1,8 | 12 |
| 4b | 10 | 26 |
| 5 | >50 | 29 |
| 6a | >50 | 35 |
| 6b | >50 | 17 |
| 8 | >50 | 36 |
| 12 | >50 | >100 |
| 13a | >50 | 22.5 |
| 13b | >50 | 13 |
